Ferriss et al. recently found that exposure to the naturally produced neurotoxin domoic acid (DA) through the recreational razor clam (Siliqua patula) fishery in Washington State may be larger than previously thought. DA is a neurotoxin naturally produced by phytoplankton and that accumulates in seafood during harmful algal blooms. As the prevalence of DA increases in the marine environment, there is a critical need for better data to assess potential risks to human health through DA exposure. During the Winter 2015 and Spring 2016 clamming seasons we distributed surveys to recreational harvesters to determine razor clam consumption in this population. Combining this consumption data with actual DA measurements in razor clams measured by the state monitoring program we estimated the amount of DA a person would consume if they harvested and ate razor clams from the Washington Coast. Human exposure to DA was well within the regulatory limits for the majority of recreational clam harvesters. However, approximately seven percent of total acute exposures (exposures after a single meal of clams) calculated exceeded the level advised in current regulations, In addition, three percent of survey respondents were potentially at risk of chronic DA exposure defined as consuming a minimum of 15 clams per month for 12 consecutive months. This study contributed to the development of a razor clam consumption advisory in Washington State for chronic exposure and identified demographics of recreational clam harvesters who may be at risk of acute DA exposure. Although DA monitoring has prevented acute toxic events, these data point to the need to better understand the potential for more subtle effects of DA exposure on human health to better manage potential public health risks associated with seafood consumption.