Abstracts

Peer-Reviewed Conference Proceedings and Abstracts

2014
58. Lugo J, Thompson MH, Huber P, Smith G, Holley A, Bain SD, Gardiner EM, Kwon RY. Neuron subset specific PTEN deletion induces abnormal skeletal activity in mice. American Epilepsy Society Annual Meeting 2014Oral Presentation
57. Kwon RY, Virdi A, Sumner DR. Cross-species transcriptomic analysis reveals conserved osteogenic signatures during zebrafish and rat bone regeneration. American Society for Bone and Mineral Research Annual Meeting 2014.
56. Kwon RY, Recidoro AM, Kaminsky W. Rotopol and microCT imaging in the regenerating zebrafish fin for BMD therapeutic discovery. American Society for Bone and Mineral Research Annual Meeting 2014.
55. Thompson MH, Huber P, Smith G, Holley A, Bain SD, Gardiner EM, Lugo J, Kwon RY. Brain-specific PTEN deletion induces abnormal skeletal activity in mice. American Society for Bone and Mineral Research Annual Meeting 2014.
54. Worton LE, Park B, Recidoro AM, Gardiner EM, Kwon RY. Sensory neuron differentiation enhances osteoblast differentiation through soluble factors. American Society for Bone and Mineral Research Annual Meeting 2014.
53. Bain SD, Huber P, Kwon RY, Stoll L, Gross TS. Muscle, bone, and nerve differentially interact to achieve trabecular and cortical bone homeostasis. American Society for Bone and Mineral Research Annual Meeting 2014Plenary Oral Presentation
52. Recidoro AM, Kaminsky W, Kwon RY. Bone mineralization in the regenerating zebrafish fin. 11th International Conference on Zebrafish Genetics and Development 2014.
51. Petrie TA, Strand NS, Recidoro AM, Gutgsell A, Kwon RY, Moon RT, Neuronal signaling is necessary for zebrafish appendage regeneration. 11th International Conference on Zebrafish Genetics and Development 2014. Plenary Oral Presentation
50.  Roof AC, Recidoro AM, Ausk BJ, Srinivasan S, Gross TS, Gardiner EM, Bain SD, Allan CH, Kwon RY, Chemical and mechanical nerve Impairment inhibit joint specification and bone formation in the regenerating zebrafish fin. Trans Orthopaedic Research Society 2014. Oral Presentation
49.  Ausk BJ, Worton LE, Threet D, Kwon RY, Bain SD, Gardiner EM, Gross TS, Transient muscle paralysis predisposes bone marrow to formation of giant osteoclasts. Trans Orthopaedic Research Society 2014.
48.  Stoll L, Huber P, Kwon RY, Threet D, Gross TS, Bain SD, Contralateral bone loss following ipsilateral nerve injury: Evidence for a neuronal skeletome. Trans Orthopaedic Research Society 2014.

2013
47.  Huber P, Ausk BJ, Gardiner EM, Bain SD, Srinivasan S, Gross TS, Kwon RY, Systems-based discovery in the zebrafish skeleton using micro-computed tomography. 8th European Zebrafish Meeting 2013. Plenary Oral Presentation
46.  Kwon RY, Mapping the skeletal connectome: Emergent bone signatures following neuronal dysfunction in zebrafish. Sun Valley Workshop 2013. Oral Presentation, Harold M. Frost Young Investigator Award
45.  Recidoro AM, Roof AC, Ausk BJ, Srinivasan S, Gardiner EM, Gross TS, Bain SD, Allan CH, Kwon RY, Neuroskeletal signaling in the regenerating zebrafish fin: Remote inhibition of osteoblast function via disruption of cholinergic signaling. American Society for Bone and Mineral Research Annual Meeting 2013. Plenary Poster and Oral Presentation
44.  Huber P, Ausk BJ, Gardiner EM, Bain SD, Srinivasan S, Gross TS, Kwon RY, The skeleton as a complex system: Emergent bone loss signatures following neuromuscular injury in zebrafish. Biomedical Engineering Society Annual Meeting 2013. Oral Presentation
43.  Kwon RY, Threet D, Gardiner EM, Worton LE, Gross TS, Srinivasan S, Timed administration of Cyclosporin A supplements reveals multiple routes to rescuing loading-induced bone formation at senescence. Biomedical Engineering Society Annual Meeting 2013. Oral Presentation
42.  Worton LE, Srinivasan S, Kwon RY, Fluid dynamic gauging-based assays for high-throughput investigation of cellular mechanotransduction. ASME Summer Bioengineering Conference 2013, 14394.
41.  Downey LM, Gross TS, Kwon RY, Differential expression of osteoactive myokines and muscle-enriched microRNAs following transient muscle paralysis. Trans Orthopaedic Research Society 2013, 1440.
40.  Srinivasan S, Prasad J, Ausk BJ, Kwon RY, Worton L, Gross TS, Bain SD, Gardiner EM, Concurrent optimization of Cyclosporin A and mechanical loading identifies multiple optima to rescue senescent bone adaptation. Trans Orthopaedic Research Society 2013, 1421.

2012
39.  Kwon RY, Worton LE, Srinivasan S, Gross TS. Differential expression of transcriptional clusters and recurring ERK1/2 activation in bone cells subjected to rest-inserted dynamic fluid flow. Trans Orthopaedic Research Society 2012, 44. Oral Presentation
38.  Worton LE, Kwon RY, Gardiner EM, Gross TS, Srinivasan S. Cyclosporin A synergistically enhances acute gene expression and differentiation in MC3T3-E1 cells subjected to dynamic fluid flow. Trans Orthopaedic Research Society 2012, 1381.
37.  Sanyal A, Keaveny T, Gupta A, Bayraktar HH, Kwon RY. Shear strength behavior of human trabecular bone. Trans Orthopaedic Research Society 2012, 125. Oral Presentation
36.  Gross TS, Ausk BJ, Bain S, Downey L, Gardner E, Kwon RY, Worton LE, Srinivasan S. Muscle atrophy enhances bone anabolism. American Society for Bone and Mineral Research Annual Meeting 2012. Oral Presentation
35.  Srinivasan S, Threet D, Ausk BJ, Worton LE, Kwon RY, Gardiner EM, Bain S, Gross TS. Tailored drug-loading interactions can rescue bone adaptation at senescence. American Society for Bone and Mineral Research Annual Meeting 2012.

2011
34.  Kwon RY, Meays DR, Meilan AS, Miramontes R, Kardos N, Yeh JC, Frangos JA. Osteocyte-independent mechanotransduction of interstitial fluid flow. Trans Orthopaedic Research Society 2011, 229. Oral Presentation
33.  Worton LE, Kwon RY, Gardiner EM, Gross TS, Srinivasan S. Fluid flow-induced early response genes are selectively altered by age. American Society for Bone and Mineral Research Annual Meeting 2011.

2010
32.  Kwon RY, Meays DR, Meilan AS, Miramontes R, Kardos N, Yeh JC, Frangos JA. Osteocyte-independent mechanotransduction of interstitial fluid flow. International Bone Fluid Flow Workshop 2010. Oral Presentation, Young Investigator Award
31.  Kwon RY, Meays DR, Meilan AS, Kardos NL, Frangos JA. Osteocyte-independent mechanotransduction of interstitial fluid flow. American Society for Bone and Mineral Research Annual Meeting 2010, JBMR 25:S19. Oral Presentation, Young Investigator Award
30.  Kwon RY, Meays DR, Kardos NL, Frangos JA. Regulation of energy metabolism by osteocytes. American Society for Bone and Mineral Research Annual Meeting 2010, JBMR 25:S220.
29.  Kwon RY, Meays DR, Meilan AS, Kardos NL, Frangos JA. Osteocyte-independent mechanotransduction of interstitial fluid flow. Sun Valley Workshop on Musculoskeletal Biology 2010. Oral Presentation

2009
28.  Kwon RY, Meays DR, Frangos JA. Microfluidic enhancement of skeletal fluid flow inhibits hindlimb unloading-induced bone loss in mice. Society for Physical Regulation in Biology and Medicine 2009. Oral Presentation
27.  Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Adenylyl cyclase 6 and cAMP mediate primary cilia-dependent mechanosensing in bone cells. Society for Physical Regulation in Biology and Medicine 2009. Oral Presentation
26.  Kwon RY, Meays DR, Frangos JA. Microfluidic enhancement of intramedullary pressure increases interstitial fluid flow and inhibits hindlimb unloading-induced bone loss in mice. Biomedical Engineering Society Annual Meeting 2009. Oral Presentation
25.  Melchior, B, Kwon RY, Frangos JA. Inter-endothelial junctional inclination determines flow direction sense in endothelial cells. Biomedical Engineering Society Annual Meeting 2009. Oral Presentation
24.  Kwon RY, Meays DR, Frangos JA. Microfluidic enhancement of intramedullary pressure increases interstitial fluid flow and protects against hindlimb unloading-induced bone loss in mice. American Society for Bone and Mineral Research Annual Meeting 2009, JBMR 24:S101. Plenary Poster Presentation
23.  Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Adenylyl cyclase 6 mediates primary cilia-dependent changes in cyclic adenosine monophosphate in response to dynamic fluid flow. ASME Summer Bioengineering Conference 2009.
22.  Kwon RY, Meays DR, Frangos JA. Oscillatory intramedullary pressure generated by a novel microfluidic system enhances interstitial transport and inhibits hindlimb unloading-induced bone loss in mice. New York Skeletal Biology and Medicine Conference 2009.

2008
21.  Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Adenylyl cyclase 6 mediates primary cilia-regulated decreases in cAMP in bone cells exposed to dynamic fluid flow. American Society for Bone and Mineral Research Annual Meeting, 2008, JBMR 23:S13. Oral Presentation
20.  Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Investigating the role of primary cilia in oscillatory fluid flow-induced increases in intracellular cAMP levels in MC3T3-E1 osteoblastic cells. Trans Orthopaedic Research Society 2008. Oral Presentation
19.  Kwon RY, Temiyasathit S, Tummala P, Quah CC, Jacobs CR. Primary cilia mediate intracellular cAMP responses in bone cells exposed to dynamic fluid flow. ASME Summer Bioengineering Conference 2008, 192511. 2nd Place PhD Student Paper Competition
18.  Kwon RY, Quah, CC, Jacobs CR. Computational models of fluid flow through the osteocyte pericellular space show substantial loading on their cell bodies due to pressure gradients. Trans Orthopaedic Research Society 2008.

2007
17.  Kwon RY, Jacobs CR, Lew AJ. A microstructurally informed model for the three-dimensional mechanical response of actin networks. US National Congress on Computational Mechanics 2007. Oral Presentation
16.  Kwon RY, Jacobs CR. Viscoelasticity of bone cells exposed to fluid flow in vitro. Trans Orthopaedic Research Society 2007, 150. Oral Presentation
15.  Johnston TR, Kwon RY, Jacobs CR. Side view characterization of bone cells and their primary cilia using adapted fluid flow chamber. Trans Orthopaedic Research Society 2007, 147. Oral Presentation
14.  Clowes EJ, Kwon RY, Tummala P, Carter DR, Jacobs CR. Role of cytoskeletal tension in osteogenesis due to loading induced fluid flow. Trans Orthopaedic Research Society 2007, 150. Oral Presentation
13.  Kwon RY, Jacobs CR. Viscoelasticity of bone cells exposed to fluid flow in vitro. Society for Physical Regulation in Biology and Medicine 2007. Oral Presentation, Best PhD Student Presentation
12.  Doll JC, Harjee N, Klejwa N, Kwon RY, Coulthard S, Pruitt BL. Biological measurements of C. Elegans touch sensitivity with microfabricated force sensors. MicroTAS 2007, 0896.
11.  Klejwa N, Harjee N, Kwon RY, Coulthard S, Pruitt BL. Transparent SU-8 three-axis micro strain gauge force sensing pillar arrays with biological applications. Transducers 2007, AM0261.

2006
10.  Kwon RY, Jacobs CR, Lew AJ. Homogenization of the actin cytoskeleton: An approach based on finite element analysis, microstructure characterization and weighted principal component analysis. Trans Orthopaedic Research Society 2006, 363. Oral Presentation
9.  Kwon RY, Ayeni, OA, Jacobs CR. Investigation of the mechanics of bone cells exposed to fluid flow. Trans Orthopaedic Research Society 2006, 129. Oral Presentation
8.  Kwon RY, Ayeni, OA, Jacobs CR. Mechanics of deformation of osteoblastic cells exposed to steady and oscillatory fluid flow. Society for Physical Regulation in Biology and Medicine 2006.
7.  Kwon RY, Jacobs CR, Lew AJ. A novel approach to image based modeling of the actin cytoskeleton. ASME Summer Bioengineering Conference 2006.

2005
6.  Kwon RY, Abad-Manterola P, Lew AJ, Jacobs CR. Computational modeling of actin networks and the cytoskeleton. Society for Physical Regulation in Biology and Medicine 2005. Oral Presentation, Best PhD Student Presentation
5.  Kwon RY, Jacobs CR, Lew AJ. Computational modeling of actin networks. ASME Summer Bioengineering Conference 2005.
4.  Kwon RY, Ayeni, OA, Jacobs CR. Mechanics of deformation of bone cells. Biomedical Computation at Stanford 2005.

2004
3.  Kwon RY, Abad-Manterola P, Jacobs CR, Lew AJ. Computational modeling of actin networks and the cytoskeleton. California Tissue Engineering Annual Meeting 2004. Oral Presentation

2003
2.  Bayraktar HH, Gupta A, Kwon RY, Keaveny TM. Multiaxial failure behavior of human femoral trabecular bone. Trans Orthopaedic Research Society 2003, 202. Oral Presentation

2002
1.  Keaveny TM, Bayraktar HH, Kwon RY. Shear loading is the weakest link for femoral neck trabecular bone. Trans Orthopaedic Research Society 2002, 555.