2019 Lecture/Exercise 4.6

Lecture/Exercise 5.1

Making sense of your output: assessing confidence in model selection and parameters

Marguerite Butler


Lecture projections

Some thoughts on development and limitations on applying the OU models, and some recommendations on how to interpret results.


Testing Adaptation with Evolutionary Models
Massive Simulation Take Aways

Exercise materials



Audio recording




A Few References

Ané C. 2008. Analysis of comparative data with hierarchical autocorrelation. Ann. Appl. Stat. 2:1078–1102.

Boettiger C., Coop G., Ralph P. 2012. Is your phylogeny informative? Measuring the power of comparative methods. Evolution 66: 2240–2251.

Bonine K.E., Gleeson T.T., and Garland T. 1999. Sprint performance of phrynosomatid lizards, measured on a high-speed treadmill, correlates with hindlimb length. J. Zool. 40: 1–18.

Cressler C., Butler M.A., and King A. A. 2015. Detecting adaptive evolution in phylogenetic comparative analysis using the Ornstein-Uhlenbeck model.  Sys. Bio. 64(6):953-968. DOI: 10.1093/sysbio/syv043

Ho L.S.T., Ané C. 2013. Asymptotic theory with hierarchical autocorrelation: Ornstein-Uhlenbeck tree models. Ann. Stat. 41:

Scales J.A., King A.A., and Butler M.A. 2009. Running for your life or running for your dinner: What drives fiber type evolution in lizard locomotor muscles? Am. Nat. 173: 543–553.

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