Bringing New Therapies to the Bedside
All new therapies, biomarkers or other medical discoveries must be tested in patients through clinical trials. This complex and demanding process requires a high degree of compassion and medical expertise, as well as communication and organizational skills. Thus many specialized experts working closely as a team.
The IPCR has two integrated clinical trials teams: one focused on developing and testing therapies for advanced disease; and the other developing and testing therapies designed to be used with surgery and radiotherapy for treating localized prostate cancers (those in which tumors are only in the prostate and have not spread to other organs in the body).
Many of the clinical trials are unique to Seattle. Several new research studies, called novel studies, involve the first evaluation of new therapeutic treatments in people. Other trials involve more than one research institution and originate through cooperation with leading national clinical trials groups involving the major cancer centers in the United States and abroad.
IPCR clinical trials include some of the most innovative therapies currently being evaluated nationally. The institute includes one of 10 National Cancer Institute-funded prostate cancer Specialized Programs of Research Excellence (SPORE). As a result, IPCR physicians participate in new therapy trials often available only to that group, allowing UW Medicine patients to receive new, better treatments as quickly as possible.
IPCR clinical trials researchers are also members of the Department of Defense Prostate Cancer Clinical Trials Consortium and have access to many trials conducted by this special group of 12 leading prostate cancer centers in the United States.
Our clinical trial accomplishments
Molecular Studies in localized disease:
- Neoadjuvant therapy, giving other treatments before the traditional primary treatment for a localized disease, has improved the outcomes of many cancer patients. In the past, these therapies have been slow to reach many cancer patients because their success could be judged only after many years of follow-up and study.
IPCR researchers have helped pioneer a new, quicker approach for evaluating neoadjuvant therapies. At the time of the primary surgery or just before radiation therapy, physicians take a cancer specimen for molecular analysis. In this way, scientists are able to tell more quickly whether a new therapy is effective by looking at the way molecules in the cancer specimen react to the therapy.
- So far, the IPCR team has conducted large neoadjuvant molecular studies of chemotherapy drugs and, more recently, of newer hormone therapies. Many more molecular neoadjuvant studies are in the planning stages.
- Every tumor (and patient) has unique characteristics, dictated by gene variations. The molecular analyses of cancers provide an opportunity for researchers to develop a personalized approach to treating and following a patient’s particular cancer.
Innovative treatments for advanced disease:
- Although suppressing testosterone and administering chemotherapy prolong survival for men with advanced prostate cancer, most cancers eventually develop resistance to these interventions. IPCR investigators have conducted Phase I, first-in-human, trials designed to block tumors’ resistance mechanisms, allowing patients in the Northwest to be the first recipients of treatments resulting from these promising laboratory findings.
- Encouraging results from novel studies involving antibodies targeting the Insulin-like Growth Factor-1 Receptor (IGF-1R) and small molecules targeting the stress response protein clusterin, have led to clinical trials designed to substantially improve the longevity of men with advanced prostate cancer.
- IPCR investigators are also key participants in trials involving new effective therapies developed elsewhere, such as Provenge, abiraterone, and MDV-3100.
Hy, you write very well its appreciated by me and my fellow. Thanks
Hy you did very well. It’s a very kind job I want to share this with my contacts also desire a seminar with our Organization Zameenforyou with the cooperation of you. Thanks.
Hy you did very well. It’s a very kind job I want to share this with my contacts also desire a seminar with our Organization Zameenforyou.com with the cooperation of you. Thanks.
Hy you did very well. It’s a very kind job I want to share this with my contacts also desire a seminar with our Organization ‘Zameenforyou.com’ with the cooperation of you. Thanks.
It is actually a nice and helpful piece of info.
Thanks for sharing such info and we still need to improve it
https://saynotodisease.com/
Thanks for sharing such info and we still need to improve it
saynotodisease.com
very nice article.. this is useful post . thanks alot for sharing a post realted to new therapies on bedside.
Hi!
Your style is so unique compared to many other people. Thank you for publishing when you have the opportunity, Guess I will just make this bookmarked.
More Information : https://www.boostlize.com/
No. 1 Online Book Store in Pakistan,
Thanks for sharing.
http://kitabread.com/product-category/self-help-books/
Buy UK Twitter Followers or global, Facebook Likes, Instagram Followers at fair prices. YouTube subscribers, views also available on your desired amount. SoundCloud services with amazing packages.URL required only. 24/7 customer support. Read our blog to learn how to get more traffic on your social media profiles.
Buy YouTube views here for online video sharing platform for earning and marketing. Get more likes on videos and subscribers for channels. Both worldwide and UK based services. Fair prices with discount packages. Secure Payment through PayPal. no access required. Just sent URL of post or channel. Guaranteed secure services with 24/7 active customer support.
i really this website thanks for sharing
HI,
Thank you so much for doing great info. i’m also see your another blog your all blog is really brilliant
good job awesome content available here really informative
http://diyarbakirevdeneve.gen.tr
I’m impressed with your true talent for writing. It’s great to find a great article. I was motivated to tell you I appreciate your work.
nice artical. thanks for sharing such a nice information.
Hey there you write very gratefully. I appreciate you and I try to share this article my all freinds
You have a real skill for writing unique content. I like how you think and the way you characterize your views in this article. I approve with your way of thinking. Thank you for sharing.
Very nice list of your blogs, Thanks
Thanks for sharing:
Best information I will tweet to my friends to get them to check it out. keep it up. Thanks for sharing!
Best collection of UK day images, UK day quotes, USA day wishes, hello, messages and UK day 2017 obscures for sharing on Facebook, what Sapp and other social media
Reparacion de aire acondicionado en Madrid, en la compañía, nos dedicamos a la reparaciones cointra de aire acondicionado, instalación y también efectuamos el mantenimiento de aire acondicionado familiar y también industrial, hacemos reparaciones de aparatos de aire acondicionado por conductos, reparación de fugas de gas y cargas de gas.
Great clinic trial accomplishments. More research and effort needed to improve the further process.
http://kratomguides.com
We see your weblog is very great to me. I have hope that u can keep up this good job. can you please also take a look at my site ?
I happen to be commenting to make you understand what a incredible discovery my girl obtained viewing yuor web blog. She picked up too many details, including what it’s like to possess a wonderful giving spirit to let the mediocre ones without difficulty learn chosen multifaceted topics. You really did more than people’s expectations. I appreciate you for producing the practical, healthy, edifying and easy thoughts on that topic to Julie.
Hi there, You’ve done a great job. I’ll definitely digg it and personally recommend to my friends. I’m sure they will be benefited from this web site.
What i don’t realize is if truth be told how you are not actually a lot more smartly-favored than you may be now. You are very intelligent. You realize thus significantly when it comes to this matter, produced me in my opinion imagine it from numerous varied angles. Its like women and men are not interested until it’s something to do with Lady gaga! Your individual stuffs outstanding. All the time care for it up!
It is actually a nice and helpful piece of info. I am satisfied that you simply shared this helpful information with us. Please stay us informed like this. Thank you for sharing.
I gotta favorite this website it seems very useful extremely helpful
I went over this web site and I think you have a lot of superb information, saved to favorites (:.
I think this is among the most significant info for me. And i am glad reading your article. But wanna remark on few general things, The website style is perfect, the articles is really excellent : D. Good job, cheers
obviously like your web-site however you have to test the spelling on several of your posts. A number of them are rife with spelling issues and I to find it very troublesome to tell the truth nevertheless I will definitely come back again.
We’re a bunch of volunteers and starting a new scheme in our community. Your website provided us with valuable information to paintings on. You have done a formidable task and our entire group can be thankful to you.
It’s actually a nice and useful piece of info. I am glad that you shared this helpful information with us. Please keep us informed like this. Thanks for sharing.
Youre so cool! I dont suppose Ive read something like this before. So nice to seek out somebody with some unique thoughts on this subject. realy thank you for beginning this up. this web site is something that’s wanted on the web, somebody with a bit originality. helpful job for bringing something new to the web!
I’ll right away grab your rss feed as I can’t find your email subscription link or newsletter service. Do you have any? Please let me know in order that I could subscribe. Thanks.
That is the appropriate blog for anyone who needs to seek out out about this topic. You notice a lot its almost hard to argue with you (not that I really would need…HaHa). You undoubtedly put a brand new spin on a topic thats been written about for years. Great stuff, simply great!
naturally like your web-site but you need to check the spelling on quite a few of your posts. Several of them are rife with spelling problems and I find it very bothersome to tell the truth nevertheless I’ll certainly come back again.
http://irkg.org/
http://stealmystuff.org/
Hi there, You have done an excellent job. I will certainly digg it and in my view recommend to my friends. I am sure they will be benefited from this web site.