For the question of whether lung cancer screening in high risk patients causes more good than harm, check out this article.

I’m pretty convinced the data shows that in a research study high risk population where the scans are read by highly skilled experts closely following the rules, lives are saved by CT screening and the cost is reasonable for each QUALY.

Further, the interpretation of these chest CT screening exams is fairly straightforward for experienced and trained radiologists. That suggests that when CT screening is extended beyond research to broader community practice, results should also be good.