Research Opportunity: Studies of the biology and pathogenesis of a bacterial carcinogen

Con­tact Name: Nina Salama

Con­tact Email: nsalama[at]fhcrc.org

Depart­ment: Microbiology

Descrip­tion:

The bacterial pathogen Helicobacter pylori chronically colonizes the stomach of 50% of the human population. While many remain asymptomatic, this infection is the major risk factor for development of ulcers and stomach cancer. The Salama is interested in the mechanisms by which this bacterium can establish and maintain a chronic infection in the unusual environment of the human stomach and the molecular cross talk between the host and the bacteria during the decades long infection. Current lab projects include studies on the cause and consequence of genetic variation during chronic infection and the molecular mechanism underlying this bacterium’s unique helical morphology.
We are presently seeking an undergraduate with a strong interest in microbiology and molecular biology and who is looking to gain experience working in a lab. Specifically, we are looking for someone to perform routine PCR, DNA sequencing and bacterial transformations. This person will also have the opportunity to assist and interact with all members of the lab and learn additional techniques. Over time and with experience, this person may be able to work on a dedicated project of their own. We are looking for someone available for ~10-15 hours each week. This is an unpaid position but is an outstanding opportunity to participate in engaging and important research.

Require­ments:

10-15 hours a week
Course work/familiarity in some of the following: molecular biology, genetics, microbiology, biochemistry

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