Research Opportunity: Mechanisms of Mitochondrial Longevity Mutants

Con­tact Name: Dr. Jafari

Con­tact Email: celltimer[at]

Depart­ment: Pathology


I am a postdoctoral fellow in the Kaeberlein lab, looking for an enthusiastic and hard working student who wants to expand his/her knowledge and gain laboratory experiences and enjoy finding answers to some biological questions.

This position is not a paid position, but you can receive credit and your contribution will be appreciated by mentioning in the authors section of to be published paper(s).

The project is on the role of the mitochondria in longevity and development. My team is dissecting the mechanisms by which mitochondrial electron transport chain (ETC) dysfunction result in slowing aging (longevity). In the first step, we are using EMS/ENU mutagenesis suppressor screen to detect the genetic pathways that are involved in the developmental delay in isp-1(qm150). Having success in the mutagenesis suppressor screen, we expand our knowledge in molecular mechanisms that regulate the isp-1(qm150) and other ETC mutants development and lifespan.

Research in the Kaeberlein Lab is focused on developing therapies for age-associated diseases by targeting the pathways that regulate aging. I use the nematode Caenorhabditis elegans that is considered as one of the best studied invertebrate aging models. Our lab has a very happy, friendly, supportive, and productive atmosphere.

I have around 10 years experience in C. elegans field and I can teach my skills from basic nematode maintenance, making double or triple mutants, behavior analyses, immunostaining, to microscopy and molecular biology to you. In addition, I have done medicine and can relate the knowledge of invertebrate organisms to human.


At least six months experience of biological science laboratory work (not lab courses)
Or a student who has an award or scholarship ending this year or 2015 (regardless of previous lab experience)

To apply, see application requirements via this post­ing in the database.