Tag Archives: biochemistry

Research Opportunity: Protein Therapy for Cardiac and Skeletal Muscle Disease

Con­tact Name: Wei-Ming Chien

Con­tact Email: chienw[at]uw.edu

Depart­ment: Cardiology

Descrip­tion:

Our research goal is to develop novel protein-based therapies for cardiac and skeletal muscle disorders, to be tested in cell culture and live mouse models.  Students will work with a graduate student and post-doc in the lab to assist with experimental material preparation, particularly protein induction and purification.  Applicants should provide the following information in no more than a few sentences per question.

1) Contact information (name, email or phone):
2) Current Program of Study and Year:
3) Why are you interested in this position?
4) Past lab experience if any, describe briefly:
5) What do you hope to gain from working in the Chin Lab?
6) What are your hobbies?
7) Where do you hope to be in:
a. 5 years from now?
b. 10 years from now?
8) What are your strengths and weaknesses?
9) What is your availability in terms of time per week and duration of commitment?

Require­ments:

The student should commit for at least one year.  Hours spent in lab can be registered for undergraduate research credit.  Previous coursework in Chemistry or Biochemistry or lab experience are preferred but not required.

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Research Opportunity: Neurobiology of Drug Addiction

Con­tact Name: Dr. C Chavkin

Con­tact Email: cchavkin[at]uw.edu

Depart­ment: Pharmacology

Descrip­tion:

The lab is funded to study how stress increases the risk of drug addiction at the cellular, molecular and behavioral levels.  We use western blots, cell culture, simple mouse behavioral approaches.

We have opportunities for responsible and advanced undergraduates to learn research techniques by assisting a graduate student and a post doctoral fellow in their research. These are volunteer projects.

We also have a paid lab assistant (hourly) job for someone interested in helping us care for mice and do PCR genotyping.

Require­ments:

  • Biochemistry
  • Science GPA >3.4
  • Willingness to commit to working >10hrs/wk and for at least 2 quarters (hopefully 4)

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Research Opportunity: The role of mitochondria and metabolism in the development of human diseases

Con­tact Name: Rong Tian

Con­tact Email: rongtian[at]uw.edu

Depart­ment: Anesthesiology, Bioengineering, Biochemistry

Descrip­tion:

We are looking for students to work with mouse models of altered mitochondrial function and/or cell metabolism to investigate disease mechanisms.  The student will be involved in treatment of mouse models, monitoring physiological function of multiple organ systems, and biochemical analysis of tissue samples.  Molecular and genetics analysis will be included in the later stage of the project.

Require­ments:

Comfortable to work with animals.
General knowledge of biology, biochemistry and physiology.
A minimum of 10 hours per week needed.

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Summer Research: UT-Knoxville Dept of Biochemistry and Cellular and Molecular Biology

Department of Biochemistry and Cellular and Molecular Biology

Sensing and Signaling in Biological Systems

Research Experience for Undergraduates (REU)

The BCMB Department at UT-Knoxville will once again offer a special REU program for undergraduates interested in hands-on scientific research experience.

The broad focus is on Sensing and Signaling in Biological Systems. The team of REU faculty represent multiple modern scientific disciplines including cell biology, molecular biology, genetics, biochemistry, physical chemistry, and computational biology.

We especially encourage rising sophomores and rising junior undergraduate science majors to apply.

Underrepresented minorities, women, and first generation college students are also strongly encouraged to apply. Applicants must be a US citizen or a permanent resident.

 More information and on-line applications are available at our web site at: http://web.bio.utk.edu/bcmb/summer/reu.html  or email bcmbreu@utk.edu.

Research Opportunity: Research in Drug Metabolism and Toxicity

Con­tact Name: Rheem Totah

Con­tact Email: rtotah[at]uw.edu

Depart­ment: Medicinal Chemistry

Descrip­tion:

Students will have a chance to engage in research in drug metabolism and drug toxicity involving cytochrome P450 enzymes.  Several projects are available depending on student interest to investigate the biochemical properties of CYP2J2 and CYP2C8.

Require­ments:

Complete two courses in chemistry and one biochemistry

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Research Opportunity: Studies of the biology and pathogenesis of a bacterial carcinogen

Con­tact Name: Nina Salama

Con­tact Email: nsalama[at]fhcrc.org

Depart­ment: Microbiology

Descrip­tion:

The bacterial pathogen Helicobacter pylori chronically colonizes the stomach of 50% of the human population. While many remain asymptomatic, this infection is the major risk factor for development of ulcers and stomach cancer. The Salama is interested in the mechanisms by which this bacterium can establish and maintain a chronic infection in the unusual environment of the human stomach and the molecular cross talk between the host and the bacteria during the decades long infection. Current lab projects include studies on the cause and consequence of genetic variation during chronic infection and the molecular mechanism underlying this bacterium’s unique helical morphology.
We are presently seeking an undergraduate with a strong interest in microbiology and molecular biology and who is looking to gain experience working in a lab. Specifically, we are looking for someone to perform routine PCR, DNA sequencing and bacterial transformations. This person will also have the opportunity to assist and interact with all members of the lab and learn additional techniques. Over time and with experience, this person may be able to work on a dedicated project of their own. We are looking for someone available for ~10-15 hours each week. This is an unpaid position but is an outstanding opportunity to participate in engaging and important research.

Require­ments:

10-15 hours a week
Course work/familiarity in some of the following: molecular biology, genetics, microbiology, biochemistry

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Research Opportunity: Synthetic Protein Chemistry

Con­tact Name: Champak Chatterjee

Con­tact Email: chatterjee[at]chem.washington.edu

Depart­ment: Chemistry

Descrip­tion:

The Chatterjee laboratory in the Department of Chemistry has one opening for an undergraduate student majoring in chemistry or biochemistry in the general area of peptide synthesis. Students are encouraged to apply for CHEM 399 or 499 credit and are expected to have sufficient time to devote toward performing independent research. The project revolves around applying cutting-edge chemical synthesis strategies to synthesize chemically modified polypeptides using solid-phase peptide synthesis. These synthetic peptides will be used to study the function of enzymes involved in regulating human genes.

All interested students must be at the Sophomore or Junior level and would have taken general chemistry courses.

Require­ments:

General Chemistry. Introductory Organic Chemistry preferred but not essential. Chemistry or Biochemistry majors only.

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Researcher Spotlight: Guillermo Romano

Guillermo Romano, Class of 2013

Amgen ScholarMary Gates Research Scholar, and Undergraduate Research Leader

Majors: Biochemistry, Public Health
Minor: Chemistry
Research Mentor: Dr. Dustin Maly

Where is Guillermo now?
Guillermo is currently doing research at Seattle Children’s Research Institute with Dr. David Rawlings, working on a gene therapy project aimed at making human cells immune to HIV infection.