Tag Archives: pathology

Research Opportunity: Mechanisms of Mitochondrial Longevity Mutants

Con­tact Name: Dr. Jafari

Con­tact Email: celltimer[at]gmail.com

Depart­ment: Pathology

Descrip­tion:

I am a postdoctoral fellow in the Kaeberlein lab, http://kaeberleinlab.org/people/ali-jafari looking for an enthusiastic and hard working student who wants to expand his/her knowledge and gain laboratory experiences and enjoy finding answers to some biological questions.

This position is not a paid position, but you can receive credit and your contribution will be appreciated by mentioning in the authors section of to be published paper(s).

The project is on the role of the mitochondria in longevity and development. My team is dissecting the mechanisms by which mitochondrial electron transport chain (ETC) dysfunction result in slowing aging (longevity). In the first step, we are using EMS/ENU mutagenesis suppressor screen to detect the genetic pathways that are involved in the developmental delay in isp-1(qm150). Having success in the mutagenesis suppressor screen, we expand our knowledge in molecular mechanisms that regulate the isp-1(qm150) and other ETC mutants development and lifespan.

Research in the Kaeberlein Lab is focused on developing therapies for age-associated diseases by targeting the pathways that regulate aging. I use the nematode Caenorhabditis elegans that is considered as one of the best studied invertebrate aging models. Our lab has a very happy, friendly, supportive, and productive atmosphere.

I have around 10 years experience in C. elegans field and I can teach my skills from basic nematode maintenance, making double or triple mutants, behavior analyses, immunostaining, to microscopy and molecular biology to you. In addition, I have done medicine and can relate the knowledge of invertebrate organisms to human.

Require­ments:

At least six months experience of biological science laboratory work (not lab courses)
Or a student who has an award or scholarship ending this year or 2015 (regardless of previous lab experience)

To apply, see application requirements via this post­ing in the database.

Research Opportunity: Human immune response to viral infections

Con­tact Name: David Koelle

Con­tact Email: viralimm[at]uw.edu

Depart­ment: Medicine

Descrip­tion:

Our lab studies the immune response to several viruses that infect humans including herpes simplex types 1 and 2, the chicken pox virus, and a cancer virus also. We are interested in vaccine development, figuring out why some people get severe disease, and also technology development in decoding the immune response at the cellular and molecular level.  We work primarily with T-cells rather than antibodies. The spectrum of modern molecular and cellular research methods such as cloning, sequencing, gene expression, flow cytometry, etc. are used; our lab is generally at the BSL-2 safety level as human samples and infectious pathogens are in use.  There are about 9 people including one undergrad in the lab now. The PI is a medical doctor.  We are interested in cultivating 1-2 undergrads who might possibly be interested in staying on 1-2 years as research technologists after graduation should everything work out. But someone headed straight to further schooling is fine too. Projects would likely involve molecular cloning as this has schedule-friendly workflows. We are located at South Lake Union, with a free shuttle every 20 min to UW. Grades, math skills, work ethic important.

Require­ments:

Senior, Junior or super Sophomore.  Organic lab.  Usual computer skills with programming a plus.  Decent grades. Interest in microbiology and immunology.  Some micro or immunology coursework a plus. Familiarity with bioinformatics or next-generation DNA sequencing would be a real plus; interest in taking coursework relevant to this area during the time period of the undergrad experience would be a good fit.  Students with a real interest in investigative medicine rather than “checking off the research box” for professional school entry are preferred although I certainly realize this is not black and white.

View this post­ing in the database

New Fall Research Opportunities

Every fall we get many new research opportunity postings all the time. Below are the postings from the last week or so. Follow the links for more details. As always, you can browse all postings here.

  • James Lawson, Nonviolent Revolutionary
  • Sharecroppers’ Troubadour: John Handcox, the Southern Tenant Farmers Union and the African American song tradition
  • A Novel Process for Water Purification
  • Development of point-of-care diagnostic devices for the developed and developing worlds
  • Effect of requirement for prior insurance clearance on accrual of patients onto clinical trials for acute myeloid leukemia (AML)
  • Closed Ecological Systems–Aquatic
  • Diversity and Teamwork Study
  • Stem cells as drug discovery agents
  • Transplant Surgery
  • Regulation of Macrophage Activation
  • Web-based Adolescent Health Screening and Risk Prevention
  • Medical Tricorder Project
  • Echocardiographic assessment of the structure and function of the normal and abnormal heart
  • Foster Business School Laboratory – 2 Research Assistants Needed
  • Manipulations of host cells by Chlamydia trachomatis
  • Local anesthesia in dentistry; techniques
  • Ultrasound imaging in dentistry
  • Human Immunology of Tuberculosis
  • Marketing/Social Media Research for Computer Experts
  • Sequencing Treatments for Mothers with ADHD and Their At-Risk Children
  • Myogenic stem cells: basic biology and applicability to muscle wasting disorders (muscular dystrophy) and age-associated muscle deterioration (sarcopenia)
  • Maternity, neonatal, Women’s health
  • Human Prostate Cancer Progression, Fred Hutch
  • Zebrafish models of heart and muscle disease
  • Oceanography research cruise
  • Undergraduate Research Assistant in Traumatic Brain Injury Lab
  • Learning in Biology
  • Platelet hyper-reactivity Cross talks between inflammation and hemostatic signals
  • Oral health and disease
  • Molecular Signaling Mechanisms of Heart Disease
  • Controlled fusion research in the HIT program
  • Blood-brain barrier in disease
  • Mouse genetics, cognition and Parkinson’s disease
  • Social Development in Childhood